1.) N-morpholinyl lysergamide (hemifumarate) “LAMo” – 10mg | #172a
10mg N-morpholinyl lysergamide hemifumarate, "LSM-775", "LAMo"
..."The two ethyl groups were incorporated into ring structures such as the pyrrolidide, piperidide, and morpholide, shown above, but these also had reduced anti-serotonin and psychedelic effects (Cerletti and Doepfner 1958). Although the morpholide had less than one-tenth of the potency of LSD in blocking the action of serotonin, it did however have nearly 75% of the potency of LSD as a psychedelic (Gogerty and Dille 1957).
For lysergic acid amides where only one alkyl chain was attached (e.g. lysergic acid monoethylamide), relative antiserotonin activity was related to the length of the alkyl chain. Activity increased with chain length to a maximum of 75% of the potency of LSD with the n-pentylamide (five carbon atoms in a chain) (Cerletti and Doepfner 1958)."...
Ref.: Nichols, LSD and Its Lysergamide Cousins (https://www.heffter.org/wp-content/uploads/2020/04/chap6.pdf)
| CAS# | N/A |
| Chemical Name | N-morpholinyl lysergamide hemifumarate, LSM-775, 4-lysergic acid morpholide, 4-lysergoylmorpholine, (2E)-but-2-enedioic acid; 6-methyl-4-(morpholine-4-carbonyl)-6,11-diazatetracyclo[7.6.1.0²,⁷.0¹²,¹⁶]hexadeca-1(15),2,9,12(16),13-pentaene * 2:1 hemifumarate * |
| Packaging | cryogenic vial in opaque bag, w/ inert gas |
| Appearance | grey powder |
| Purity | ≥90% |
| Melting Point | N/A |
| Molecular Weight | 453.50g/mol |
| Molecular Formula | C24H27N3O6 |
| Solubility | DMSO, D2O, H2O, methanol/alcohol |
| Storage | Store in a tightly sealed container in a cool, dry area. |
CN1CC(C=C2C1CC1=CNC3=C1C2=CC=C3)C(=O)N1CCOCC1
InChI=1/C20H23N3O2/c1-22-12-14(20(24)23-5-7-25-8-6-23)9-16-15-3-2-4-17-19(15)13(11-21-17)10-18(16)22/h2-4,9,11,14,18,21H,5-8,10,12H2,1H3
InChIKey=OTQWCDNEJVKXKG-UHFFFAOYNA-N
For research purposes only and not for use in vivo.
HNMR: There is water in the DMSO-d6 used to dissolve the sample and pulling it in, it seemed to have made the water 3.3 peak quite large and the sample is dry. Where the peaks are, they are proportional and symmetrical and the compound identified/confirmed correct. Just a confirmatory analysis...we used our own custom synthesis procedure we developed that we became good at and consistent with.
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